Cancer Focus on Women

Is ovarian cancer relative to you? Ask your mom.

If you’ve ever had ovarian cancer, you should tell the other women in your family. Encourage them to get a genetic test done.

“A significant number of ovarian cancer cases are due to cell mutations found throughout a family’s genetic code,” said Dr. Sharad Ghamande, associate director of clinical research at the Georgia Cancer Center. “I know it’s hard to talk about cancer around the dinner table or at birthday celebrations, but by doing so you can save a life.”

Of the 22,000 women who are expected to be diagnosed with ovarian cancer in 2018, less than 40% will survive, according to the National Cancer Institute.

“A woman’s lifetime risk of developing ovarian cancer is approximately 1 in 78,” said Angela Brickle, genetics counselor at the Georgia Cancer Center. “Among all cases of ovarian cancer, 10-20 percent are due to inherited genetic changes.”

“The majority of the patients we treat have an advanced stage of ovarian cancer,” Ghamande said. “These patients have had red flags, but no one asked the right questions or had the tough conversations about their risk for ovarian cancer.”

Some red flags you should look for are:

  • Bloating
  • Pelvic, back or abdominal pain
  • A feeling of urgency; always feeling like you have to use the bathroom or feeling like you have to go more frequently.
  • Feeling full quickly when eating or trouble eating.
  • Upset stomach
  • Pain during sex
  • Constipation
  • Abdominal swelling despite weight loss
  • Changes or irregularity in your menstrual cycle

As women, we may experience any of these symptoms for normal, completely healthy, reasons. It’s important to remember that no one knows your body as well as you do. If you think you’re experiencing anything abnormal, talk to your doctor. When these symptoms are caused by cancer, they tend to occur more often, be more severe and persistent over long periods of time.

“Once you are diagnosed with ovarian cancer, you need to follow-up with a genetic counselor to get tested,” Ghamande said. “Then, you need become an advocate for the rest of the women in your family and recommend they get tested because it can be a preventable disease!”

In a genetic counseling session, personal and family history information is gathered and education is provided regarding hereditary cancer and genetic testing options. A simple blood draw or saliva sample is then collected and sent to a reputable laboratory for testing.

“Genetic counseling is essential both before and after the testing process to promote understanding of the benefits and limitations to testing in addition to gaining an accurate interpretation of results,” Brickle said. “If an individual is discovered to carry an inherited gene mutation, they receive continued support, recommendations for care, and helpful resources.”

If it’s cancer, see us first.
Our teams of specially-trained cancer providers are skilled in the care of your unique diagnosis. Every type of cancer reacts differently within your unique biological microenvironment and so our teams work together to collaborate and determine a personalized treatment plan for your individual needs. Visit or call 888-365-0747.

National Cancer Institute: Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

About the author

Augusta University Health

Based in Augusta, Georgia, Augusta University Health is a world-class health care network, offering the most comprehensive primary, specialty and subspecialty care in the region. Augusta University Health provides skilled, compassionate care to its patients, conducts leading-edge clinical research and fosters the medical education and training of tomorrow’s health care practitioners. Augusta University Health is a not-for-profit corporation that manages the clinical operations associated with Augusta University.